Endocrine factors in senile osteoporosis.

Serum1, 25-dihydroxyvitamin D •k1, 25(OH)2D•l, parathyroid hormone (PTH), calcitonin (CT), calcium, inorganic phosphorus and alkaline phosphatase (Al-P'ase) levels were determined in24patients with senile or postmenopausal osteoporosis, which was diagnosed by lateral X-ray film of lumbar vertebrae and divided into3 stages, porosis score I, II and III according to its severity. Serum calcium in osteoporotic group with porosis score II or III was within normal limits but significantly increased compared to that of the age-matched normal group. There was no significant difference in serum inorganic phosphorus and serum Al-P'ase levels between osteoporotic groups and age-matched normal group. Serum1, 25(OH)2D level determined by radioreceptor assay was significantly decreased in the osteoporotic